David Crescenzi began his studies at the Conservatory of Fermo, subsequently graduating in Piano, Instrumentation for Band, Choral Music and Choral Conducting at the Rossini Conservatory of Pesaro. For several years he was assistant and collaborator of Alessio Vlad and a pupil of Gustav Khun, of whom he attended the specialization courses at I Pomeriggi Musicali in Milan, from 1993 to 1996.
In his thirty-year career he has tried his hand as an accompanist pianist and Choir Master in various theaters and opera festivals, both in Italy and abroad and currently, as Conductor.
From 1999 to 2001 he was Altro-Choir Master at the Carlo Felice Theater in Genoa and in 2004-2005 at the San Carlo Theater in Naples.
In 1998 he began an intense collaboration with the Cairo Opera House where in 2014 he was appointed Artistic and Music Director for opera and ballet.
From 2002 to 2017 he was Music Director at the Romanian National Opera in Timișoara where he conducted works by Puccini, Verdi, Bizet, Mascagni, Leoncavallo, Bellini, Cilea and Rossini. From 2006 he began his collaboration with the National Opera of Bucarest and then he collaborated with the Budapest Opera, where he conducts almost the entire Italian repertoire.
In the 2009/10 season he began his collaboration at the Opera of Cluj-Napoca with operas by Verdi and Puccini’s La Bohéme. At the Romanian Opera in Iași he conducts operas by Mozart, Rossini, Donizetti and Verdi. Since September 2017 he is Artistic Director of the Romanian National Opera in Cluj- Napoca. Invited to the Staatsoper in Hannover, on October 2018, he conducted Madame Butterfly for 6 performances. From the 2018/19 season he is Principal Guest Director at the Deutsche Oper am Rhein in Düsseldorf.